Isotopically Labeled Compounds
Medchemexpress LLC Lauric acid-d23 | 59154-43-7 | MFCD00144567 | 98.4% | 223.46 | C12HD23O2 | 50mg
Lauric acid-d233 is the deuterium labeled Lauric acid Lauric acid is a middle chain-free fatty acid with strong bactericidal properties The EC50s for P acnes S aureus S epidermidis are 2 6 4 g/mL respectively
Medchemexpress LLC Spisulosine-d3 (ES-285-d3) | 1246298-31-6 | 99.0% | 288.53 | 1 MG
Spisulosine-d3 (ES-285-d3) is a deuterium-labeled version of Spisulosine, an antiproliferative compound derived from marine sources. It inhibits the growth of prostate PC-3 and LNCaP cells by causing intracellular ceramide accumulation, activating PKCζ, and inducing apoptosis. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Etoxazole-d5 | 98.0% | 364.44 g/mol | C21H18D5F2NO2 | 1 MG
Etoxazole-d5 is the deuterium-labeled form of etoxazole intended for use as an isotope-labeled reference in analytical and research applications. It is used as a tracer or internal standard for quantitation and environmental or metabolic studies.
- Isotope-labeled reference standard for analytical quantitation.
- Deuterated (D5) analog of etoxazole.
- Molecular weight: 364.44 g/mol.
- Chemical formula: C21H18D5F2NO2.
- Available in small-quantity packs suitable for standards (e.g., 1 mg).
Medchemexpress LLC D-leucine-d10 | 271247-12-2 | MFCD01321412 | 99.8% | 141.23 | C6H3D10NO2 | 10mg
D-Leucine-d10 is the deuterium labeled D-Leucine D-Leucine is a more potent anti-seizure agent than L-leucine D-leucine potently terminates seizures even after the onset of seizure activity D-leucine but not L-leucine reduces long-term potentiation but had no effect on basal synaptic transmission in vitro[1]
Revvity Health Sciences Inc Iodine-125 Radionuclide, 2mCi, Specific Activity: ~17Ci/mg, 0.1M NaOH (pH 12-14), Concentration: >350mCi/mL
Iodine-125 Radionuclide, 2mCi, Specific Activity: ~17Ci/mg, 0.1M NaOH (pH 12-14), Concentration: >350mCi/mL
Medchemexpress LLC Enclomiphene-d4 | 00-00-0 | 99.9% | 409.98 g/mol | C26H24D4ClNO | 5 MG
Enclomiphene-d4 is a deuterium-labeled analogue of enclomiphene provided for use as a tracer and internal standard in quantitative analytical workflows. It is intended for research applications where stable-isotope labeling improves accuracy and precision in NMR, GC-MS, and LC-MS assays.
- Deuterium-labeled internal standard for quantitative analysis by NMR, GC-MS, and LC-MS.
- High purity: 99.85%.
- Molecular formula C26H24D4ClNO and molecular weight 409.98 g/mol.
- Available in small research quantities suitable for analytical workflows.
- Includes supporting documentation such as COA, HNMR, RP-HPLC, and LCMS reports.
Cayman Chemical DarIfenacIn-d4 10mg
An internal standard for the quantification of darifenacin by GC- or LC-MS
Medchemexpress LLC Oxybutynin-d11 chloride | 1185151-95-4 | 97.4% | 5 MG
Oxybutynin-d11 (chloride) is the deuterium-labeled version of Oxybutynin chloride. Oxybutynin chloride acts as an anticholinergic agent, inhibiting vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM. Deuterium substitution, as seen in this product, has been studied for its potential to alter the pharmacokinetic and metabolic profiles of drugs.
- It is a deuterium-labeled compound.
- It serves as a tracer.
- It can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
- It is intended for research use only.
Medchemexpress LLC Mavacamten-d5 | 2453251-00-6 | 98.6% | 278.36 | 1 MG
Mavacamten-d5 is a deuterium-labeled version of Mavacamten (HY-109037), an orally active modulator of cardiac myosin. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Methionine-DL-sulfoximine | 15985-39-4 | 98.0% | 1 G
L-Methionine-DL-sulfoximine (MSX; MSO) is a highly specific and irreversible inhibitor of Glutamine synthetase (GS). It acts as a potent convulsant, primarily affecting astroglia metabolically and morphologically. This compound has been utilized to inhibit Gln-dependent ammonia-stimulated neuronal toxicity in vitro and significantly increases the release rate of fixed nitrogen in cyanobacteria. It is considered a promising candidate for research in biofertilizers and convulsive seizures (CS).
- Highly specific and irreversible inhibitor of glutamine synthetase.
- Potent convulsant affecting astroglia.
- Inhibits Gln-dependent ammonia-stimulated neuronal toxicity in vitro.
- Increases release rate of fixed nitrogen in cyanobacteria.
- Potential for research in biofertilizers and convulsive seizures.
Cambridge Isotope Laboratories N-Palmitoyl-D-sphingosine (ceramide d18 1/16 0) (unlabeled) CP 95% 0 1 mg
N-Palmitoyl-D-sphingosine (ceramide d18 1/16 0) (unlabeled) CP 95% 0 1 mg
Cambridge Isotope Laboratories L-TYROSINE (PHENOL-17O, 35-40%), 0.25 G
L-TYROSINE (PHENOL-17O, 35-40%), 0.25 G
Medchemexpress LLC L-Leucine-5,5,5-d3, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- | 538372-74-6 | 99.25% | 356.43 | 25 MG
Fmoc-leucine-d3 is a white to off-white solid that has been tested and complies with given specifications. It is consistent with structure based on 1H NMR Spectrum and LCMS analysis.
- Appearance: white to off-white solid
- 1H NMR Spectrum: consistent with structure
- LCMS: consistent with structure
- Isotopic enrichment: 99.86%
- Storage: powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 6 months, -20°C for 1 month
Cambridge Isotope Laboratories L-Citrulline (4,4,5,5-D4, 95%), 372-75-8, MFCD00064397, 0.01g
Molecular Formula C6H13N3O3, Chemical Purity 98%, Molecular Weight 175.187
Medchemexpress LLC Flumatinib-d3 | >98% | 565.61 | 1 MG
Flumatinib-d3 is deuterium labeled Flumatinib. Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRβ, and c-Kit with IC50s of 1.2 nM, 307.6 nM, and 665.5 nM, respectively.
- Deuterium labeled Flumatinib
- Orally available
- Selective inhibitor of Bcr-Abl
- Inhibits c-Abl with IC50 of 1.2 nM
- Inhibits PDGFRβ with IC50 of 307.6 nM
- Inhibits c-Kit with IC50 of 665.5 nM